The love hormone, also known as oxytocin, plays an important role in the regulation of social and maternal behavior. It is also helpful in treatment for many mental health disorders including postpartum depression.
This implies that these cells are involved in inducing maternal behavior. Besides, it confirms what many recent human studies have shown: there is a connection between altered expression of oxytocin receptors and postpartum depression.
"Many researchers have attempted to investigate the difference between the oxytocin system in females versus males, but no one has successfully found conclusive evidence until now. Our discovery was a big surprise," said Ryoichi Teruyama, LSU Department of Biological Sciences associate professor and lead researcher of the study published in the journal 'PLOS ONE'.
Postpartum depression contributes to poor maternal health and has negative effects on a child's development. Several studies have found that children of depressed mothers are at risk for a wide range of cognitive, emotional, behavioral and medical problems. Therefore, postpartum depression is a major public health concern that has significant adverse effects on both mother and child. About 10 to 20 percent of women experience postpartum depression after childbirth.
This discovery opens doors to potential new treatments and drugs for postpartum depression targeting oxytocin receptor cells. "I think our discovery could be universal to all mammals that exhibit maternal behavior, including humans," Teruyama said.